Psychedelics (e.g. LSD, mescaline, cannabis) slowing of the rate of SHT turnover in the brain of mimicking of the effect of SHT at certain synapses in the brain may be done by LSD. AN alternative, equally real but different word may take the place of present word reality due to the action of psychedelics. There is a memory for the drug induced reality after the drug effect diminishes, and both the drug-induced, and nondrug effect diminishes, and both the drug inducted, and nondrug world can be done attended to at the same time.

A structural resemblance to the catecholamine transmitters in borne by other drugs in this class, such as mescaline. Cannabis can potentiate the depressant effects of barbiturates of the excitatory action of amphetamines, in addition to also producing its own effects. About the physiological actions of cannabis itself, less is known, but it is believed that the direct action of THC on brain cells having a special affinity or chemical attraction for cannabinoids, result in the subjective feeling of being stoned.